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our mission: stop the global rise of cardiometabolic & liver diseases
Dozens of large-scale population studies throughout the world show that higher C15:0 dietary intake and blood levels are associated with lower risks of some of the world's most devastating chronic diseases.
Paired with our extensive series of studies published in Scientific Reports, evidence is mounting around C15:0 as an essential micronutrient needed to slow the global pandemics of type 2 diabetes, cardiovascular disease, and liver disease.
In addition to these long-term benefits, C15:0 may provide near-term benefits, including improved mood, lowered caloric intake, and increased fat metabolism due to its role as an activator of key receptors (called PPARs) in our body that modulate metabolism, inflammation, appetite, and mood.
Keep reading below to learn more about how C15:0 may improve your long-term and short-term health. If you want to go straight to the full peer-reviewed scientific articles, please click here.
Paired with our extensive series of studies published in Scientific Reports, evidence is mounting around C15:0 as an essential micronutrient needed to slow the global pandemics of type 2 diabetes, cardiovascular disease, and liver disease.
In addition to these long-term benefits, C15:0 may provide near-term benefits, including improved mood, lowered caloric intake, and increased fat metabolism due to its role as an activator of key receptors (called PPARs) in our body that modulate metabolism, inflammation, appetite, and mood.
Keep reading below to learn more about how C15:0 may improve your long-term and short-term health. If you want to go straight to the full peer-reviewed scientific articles, please click here.
long-term health benefits associated with C15:0
Type 2 DiabetesNumerous studies have shown that people with higher circulating C15:0 concentrations have a lower risk having or developing type 2 diabetes.
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Cardiovascular DiseaseA nested case-control prospective study involving over 25,000 individual followed for 13 years demonstrated that people with higher circulating C15:0 concentrations were less likely to develop coronary heart disease.
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MortalityA case-control prospective study involving over 14,000 individuals followed for an average of 14 years showed that people (both men and women) who had higher dietary intake of C15:0 had lower mortality rates.
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ObesityA case-control study involving 372 women showed that higher serum C15:0 concentrations are associated with lower adiposity.
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Liver DiseasePeople with higher circulating C15:0 concentrations have a lower risk of having nonalcoholic fatty liver disease (NAFLD) and severe nonalcoholic steatohepatitis.
NAFLD now affects one in four people globally. |
Lung DiseaseA cross-sectional study among patients with chronic obstructive pulmonary disease (COPD) showed a linear association between each increased milligram of dietary C15:0 ingested and improved lung function, measured as the FEV1/FVC.
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Inflammation & ArthritisA cross-sectional study involving 484 people showed that higher serum C15:0 concentrations are associated with lower pro-inflammatory states. Another study evaluating a model of arthritis demonstrated that higher C15:0 concentrations in the serum and joint fluid was associated with a lower risk of joint degradation and osteoarthritis.
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Metabolic SyndromeMetabolic syndrome is a cluster of conditions, including obesity, insulin resistance, hypertension, and dyslipidemia that is a precursor to type 2 diabetes, heart disease, and stroke. People with higher circulating C15:0 concentrations have a lower risk having or developing metabolic syndrome.
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near-term C15:0 health benefits (as a ppar alpha/delta activator)
Since C15:0 naturally binds to and activates PPAR alpha and PPAR delta receptors, the following near-term health benefits may include:
Improved mood
PPAR alpha receptors are present in key parts of the brain involved in regulation of mood and emotions. Molecules that bind to PPAR alpha receptors can cause anti-depressant effects and improve mood.
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Lowered caloric intake
PPAR alpha activators regulate body weight by suppressing appetite and decreasing one's caloric intake. Molecules that bind to PPAR alpha stimulate regions of the brain that control satiety as well as by increasing production of ketone bodies.
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Increased fat metabolism
PPAR delta receptors are present throughout our body, including our fat. Molecules that bind to PPAR delta receptors increase the burning of fat by inducing fatty acid oxidation.
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